About Dr. ALYSON Kelvin

The Research Program

Emerging viruses are a continual threat to human health. Sometimes these viruses completely change the human infectious disease landscape as they become endemic. The biggest problem facing public health is quick development of viral vaccines to manage emerging virus outbreaks and their transition into endemic pathogens.

The current focus of my research program is understanding how the host responds to infection with emerging respiratory viruses and the subsequent host immune refinement throughout subsequent virus re-exposures or vaccination. Much of my work involves the mechanisms of immune memory related to influenza virus and coronavirus infection. Understanding these mechanisms will be key to the development of the next generation of more efficacious vaccines.

project 1: Viral Immune Imprinting and Preimmunity - How is Immune Memory Established for emerging respiratory viruses?

project 2: Mechanisms of viral Vaccination - How can information from studying immune memory development aid vaccine design? - The Search for Universal Vaccines

project 3: Emerging Viruses and the host-pathogen interaction - What is next? - Let’s be ready!

SELECTED

Publications

I have published 51 peer review manuscripts in top journals such as Science, Nature Immunology, PLOS Pathogens, Journal of Virology.

PLoS Pathogens

Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses